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Fantasy Football Matchup Rankings: Best and Worst Plays for Week 12

As the fantasy football playoffs approach, nailing your weekly matchups becomes more crucial than ever. To guide you through the Week 12 slate, we’ve analyzed the numbers and highlighted the most favorable and challenging matchups at each position. Whether you’re fighting for a playoff spot or jockeying for seeding, these insights could make all the difference.

Quarterbacks to Start and Sit

If you have Justin Herbert on your roster, get him in your lineup against the Ravens. Baltimore’s pass defense has been generous lately, allowing the 5th-most fantasy points to QBs over the past five weeks. With the Chargers likely to lean on the pass in a potential shootout, Herbert is poised for a big game.

On the flip side, those rolling with Matthew Stafford may want to temper expectations or consider other options. The Eagles have clamped down on quarterbacks recently, surrendering the 2nd-fewest fantasy points to the position. With Stafford’s receiving corps still not at full strength, this shapes up as a tough spot.

Other QB Plays: Tua Tagovailoa (vs. NE), Bo Nix (at LV)

Running Backs to Ride or Hide

Giants rookie Tyrone Tracy Jr. draws a mouth-watering matchup against Tampa Bay. The Bucs have hemorrhaged points to RBs lately, especially through the air. With Tracy dominating snaps and routes out of the Giants backfield, he’s a strong RB2 with RB1 upside in this spot, even with a new QB under center.

Tracy might well be the most intriguing fantasy play considering the matchups… Expect Tracy to play a more meaningful role in the passing game in addition to his usual rushing exploits.

– Tristan H. Cockcroft, ESPN Fantasy Analyst

Meanwhile, Panthers lead back Chuba Hubbard faces the stiffest matchup an RB can draw right now in Kansas City. The Chiefs have smothered runners all season, and the potential return of rookie Jonathon Brooks only muddies the backfield waters. Consider Hubbard a low-end RB2 at best.

Other RB Plays: Kareem Hunt (at CAR), Brian Robinson Jr. (vs. DAL)

Wide Receiver Matchups to Love and Lament

Rookie wideout Quentin Johnston has thrived in plus matchups lately for the Chargers, and he gets another fantastic draw against the Ravens. With a healthy target share and the Bolts likely to air it out, Johnston is a high-upside WR2 who could easily post WR1 numbers if he hits.

Conversely, Cowboys star CeeDee Lamb could run into some turbulence against a stingy Washington pass defense. Lamb’s target volume keeps him in the WR1 mix, but the Commanders have routinely frustrated alpha wideouts of late. Don’t expect a massive ceiling game here, especially with Lamb’s QBs in flux.

Other WR Plays: Zay Flowers (at LAC), Marvin Harrison Jr. (at SEA)

Tight Ends to Pursue or Eschew

If you need a TE streamer or flier, Patriots veteran Hunter Henry fits the bill against Miami. The Dolphins have consistently coughed up production to the position, and Henry’s expanding role in a TE-friendly offense makes him a worthy plug-and-play with top-12 upside.

On the other hand, even elite options like Mark Andrews can get bottled up by the right defense. The Chargers have erased tight ends for much of the year, so Andrews may underwhelm on volume alone. He’s still a back-end TE1, but look elsewhere in DFS.

The Bottom Line

Ultimately, matchups are just one piece of the lineup puzzle. But in a week with so many stars facing tough draws, zeroing in on players in smash spots is a shrewd way to get an edge. Whether you’re starting studs in tougher matchups or rolling the dice on upside plays, keeping these rankings in mind could steer you to fantasy glory in this crucial week.